661 Effect of sun exposure on distribution of nevi and melanoma in Caucasian and skin of color individuals

Relatively little is known about clinical and epidemiologic characteristics of nevi melanoma in skin color minorities (SOCM) compared to Caucasians. We conducted a prospective study between 3/2017-8/2018 211 patients that volunteered for cancer screening examination. The distribution melanocytic neoplasms was recorded. Surveillance, Epidemiology, End Results Program (SEER) data used identify from 2000-2017. Most were sun-exposed areas (n=2,214, 66.0%) with the majority intermittent locations (63.5%; chronic sun exposure: 35.0%; non-sun-exposed: 1.5%). On average, Caucasians had 3.0 more non-sun-exposed (95% CI 2.73, 3.26, p <0.0001). SOCM 6.17 6.05, 6.31; melanomas (n=210,844, 65.2%) occurred areas. 33,000 per 100,000 CI, 32,600, 33,300; <0.0001) SOCM. African Americans only race have than chronic. Caucasian’s nevi:melanoma ratio 22 21.7, 22.3); 33.2 32.8, 33.6). In SOCM, 14 13.9, 14.1); 10.9 10.8, 11). various ratios across body exposure supports different pathways nevogenesis carcinogenesis. environmental genomic drivers warrants further study.